2. Signaling Pathways
  3. PROTAC
  4. Ligands for Target Protein for PROTAC
  5. Ligands for Target Protein for PROTAC Inhibitor

Ligands for Target Protein for PROTAC Inhibitor

Ligands for Target Protein for PROTAC Inhibitors (3):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-126534A
    Abemaciclib metabolite M18 hydrochloride 2704316-82-3 98.01%
    Abemaciclib metabolite M18 (LSN3106729) hydrochloride, the metabolite of Abemaciclib (HY-16297A), is a CDK inhibitor with antitumor activity. Abemaciclib metabolite M18 hydrochloride and a CRBN ligand have been used to design PROTAC CDK4/6 degrader.
    Abemaciclib metabolite M18 hydrochloride
  • HY-126534S
    Abemaciclib metabolite M18-d8 98.47%
    Abemaciclib metabolite M18-d8 is the deuterium labeled Abemaciclib metabolite M18. Abemaciclib metabolite M18 (LSN3106729), the metabolite of Abemaciclib (HY-16297A), is a CDK inhibitor with antitumor activity. Abemaciclib metabolite M18 and a CRBN ligand have been used to design PROTAC CDK4/6 degrader[1][2].
    Abemaciclib metabolite M18-d<sub>8</sub>
  • HY-126534
    Abemaciclib metabolite M18 2704316-81-2
    Abemaciclib metabolite M18 (LSN3106729), the metabolite of Abemaciclib (HY-16297A), is a CDK inhibitor with antitumor activity. Abemaciclib metabolite M18 and a CRBN ligand have been used to design PROTAC CDK4/6 degrader.
    Abemaciclib metabolite M18